Excerpts from the abstracts (summaries) of relevant articles
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From the National Library of Medicine online databases:
Excerpts from the abstract of the Boller article
Excerpt from the abstract of the Manuelidis article
Regarding CJD and antioxidants
Author: Boller F; Lopez OL; Moossy J
Title: Diagnosis of dementia: clinicopathologic correlations.
Source: Neurology (Neurology.) 1989 Jan; 39(1): 76-9
Affiliation: Department of Neurology, Veterans Administration Medical
Center, Pittsburgh, PA.
Excerpts from the abstract of the Boller article
(from the National Library of Medicine online databases):
Based on 54 demented patients consecutively autopsied at the
University of Pittsburgh, we studied the accuracy of clinicians in
predicting the pathologic diagnosis. ....
.... These results show that in patients with a clinical diagnosis of
dementia, the etiology cannot be accurately predicted during life.
On and after May 2, 2005, scheduled changes to be made by the National
Library of Medicine on the NLM Gateway website may affect the
accessibility of both the "Old" and the "New" Gateway websites on this
page.
To access the unabridged abstract of the (above cited) Boller article
select the following link:
Regarding the changes of May 2, 2005, I have attempted, via an
abbreviated link renewal process, to accommodate the "New" Gateway NLM
link in the following site:
NLM Gateway Expanded Item (Boller, 1989) link
renewed circa "Sat, 26 Jan 2008 06:40:46 GMT"
"Old" link:
NLM Gateway Expanded Item (Boller, 1989) link
renewed circa "Fri, 06 May 2005 09:42:36 GMT". The aforeconstructed
links apparently require renewal by the web site editor approximately every
24 hours.
If the above link has expired, i.e. if it yields a page which contains the
statement "Your previous session has expired.", then the following
procedure may be used as an alternative means of accessing the abstract:
If the three keywords "boller 1989 clinicopathologic" do not
appear in the search field of the page accessed by the above
link, paste or type them in (without the quotation marks).
Select "Perform Search" or the similar option depending on your
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Select "Display Results" or the similar option depending on
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Select "Expand Item" (or similar option). Upon performing
this selection you should have arrived at the page containing
the article abstract.
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Search terms:
boller 1989 clinicopathologic
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From the National Library of Medicine online
databases:
Author(s): Manuelidis EE ; Manuelidis L
Title: Suggested links between different types of dementias:
Creutzfeldt-Jakob disease, Alzheimer disease, and retroviral CNS
infections.
Source: Alzheimer Dis Assoc Disord (Alzheimer disease and associated
disorders.) 1989 Spring-Summer; 3(1-2): 100-9
Affiliation: Yale University School of Medicine, Section of Neuropathology,
New Haven, CT 06510.
Excerpt from the abstract of the Manuelidis article
(from the National Library of Medicine online databases):
Several lines of investigation identify common features of
Creutzfeldt-Jakob disease, Alzheimer disease, and retroviral CNS
infections. ....
An excerpt from the text of the Manuelidis article
On and after May 2, 2005, scheduled changes to be made by the National
Library of Medicine on the NLM Gateway website may affect the
accessibility of both the "Old" and the "New" Gateway websites on this
page.
To access the unabridged abstract of the (above cited) Manuelidis article
select the following link:
Regarding the changes of May 2, 2005, I have attempted, via an
abbreviated link renewal process, to accommodate the "New" Gateway NLM
link in the following site:
NLM Gateway Expanded Item (Manuelidis, 1989) link
renewed circa "Sat, 26 Jan 2008 06:55:04 GMT"
"Old" link:
NLM Gateway Expanded Item (Manuelidis, 1989) link
renewed circa "Thu, 05 May 2005 04:31:12 GMT". The aforeconstructed
links apparently require renewal by the web site editor approximately every
24 hours.
If the above link has expired, i.e. if it yields a page which contains the
statement "Your previous session has expired.", then the following
procedure may be used as an alternative means of accessing the abstract:
If the three keywords "manuelidis 1989 suggested" do not
appear in the search field of the page accessed by the above
link, paste or type them in (without the quotation marks).
Select "Perform Search" or the similar option depending on your
browser.
Select "Display Results" or the similar option depending on
your browser.
Select "Expand Item" (or similar option). Upon performing
this selection you should have arrived at the page containing
the article abstract.
National Library of Medicine Gateway Search
National Library of Medicine (old) Gateway Search
Search terms:
manuelidis 1989 suggested
National Library of Medicine (old) Gateway Search
National Library of Medicine Gateway Search
An excerpt from page 102 of the text of the aforementioned
Manuelidis article:
In our own neuropathological material, in 46 cases diagnosed
clinically as AD, 6 cases were proven to be CJD at autopsy
(unpublished data).
In the above excerpt, "AD" is an abbreviation for Alzheimer disease, and
"CJD" is an abbreviation for Creutzfeldt-Jakob disease.
The following link accesses Usenet group postings most or all of which
discuss the (above cited) Boller and Manuelidis articles:
Google Search: boller manuelidis cjd (groups.google.com)
National Library of Medicine Gateway Search
Regarding CJD and antioxidants i.e. "...the use of antioxidants in the
therapy of this disease.":
Article title: Increased lipid peroxidation in cerebrospinal fluid and
plasma from patients with Creutzfeldt-Jakob disease.
Authors: Arlt S, Kontush A, Zerr I, Buhmann C, Jacobi C,
Schroter A, Poser S, Beisiegel U.
Journal: Neurobiol Dis. 2002 Jul;10(2):150-6.
Excerpts from the article abstract:
.... To assess the role of oxidative stress in Creutzfeldt-Jakob
disease (CJD), we investigated the oxidizability of lipids, the
lipid composition and the levels of the antioxidants ascorbate and
alpha-tocopherol in CSF and plasma of 15 CJD patients and 12
neurologically healthy controls. .... .... These results support the
hypothesis that oxidative mechanisms are involved in the pathogenesis
of CJD and provide a rationale for the use of antioxidants in the
therapy of this disease.
Editor's note: The "antioxidants ascorbate and alpha-tocopherol"
referred to above are vitamin C and vitamin E respectively.
To view the entire abstract of the above article, enter the name of one of
the authors, the year of publication, and a significant word from the
article title into the search field of the NLM web site below:
National Library of Medicine Gateway Search
To view titles of other research articles which discuss both CJD and
antioxidants, enter "CJD antioxidant" (without the quotation marks) into
the search field of the "National Library of Medicine Gateway Search" link
below:
National Library of Medicine Gateway Search
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The site which you are currently reading is hosted by Grex, and edited by rksjr@cyberspace.org. Links expired or soon to expire: NLM Gateway Expanded Item (Boller 1989) link renewed: "Wed, 20 Nov 2002 01:59:33 GMT" Above link is still viable as of: "Wed, 20 Nov 2002 23:25:01 GMT" "Wed, 20 Nov 2002 23:52:05 GMT" "Thu, 21 Nov 2002 00:22:45 GMT" "Thu, 21 Nov 2002 01:08:19 GMT" "Thu, 21 Nov 2002 01:50:14 GMT". The above link was found to have expired sometime between: "Thu, 21 Nov 2002 01:50:14 GMT" and "Thu, 21 Nov 2002 01:59:07 GMT". NLM Gateway Expanded Item (cjd alzheimer) link renewed: "Sat, 29 Mar 2003 15:41:42 GMT". Link testing: NLM Gateway Expanded Item (cjd alzheimer) link renewed: "Sat, 29 Mar 2003 15:41:42 GMT". ["NLM Gateway Error"?]: NLM Gateway Expanded Item (Boller, 1989) link renewed circa "Sat, 13 Sep 2003 14:40:50 GMT" NLM Gateway Expanded Item (Boller, 1989) link renewed circa "Sat, 13 Sep 2003 14:40:50 GMT".